Colostrum and Diarrhea and AIDS

Colostrum is effective in the treatment of all kinds of diarrhea in all humans, even those with severe health challenges such as HIV. It is also effective for farm animals, and pets such as cats and dogs.

J Clin Chem Clin Biochem. 1990 Jan;28(1):19-23.
Antibodies from colostrum in oral immunotherapy.
Stephan W, Dichtelmüller H, Lissner R.

Biotest Pharma GmbH, Forschungsabteilung, Frankfurt.

An immunoglobulin preparation for oral use was prepared from pooled bovine colostrum from more than 100 animals. The preparation has high antibacterial antibody titres, and a high capacity for the neutralization of bacterial toxins. 
It is well tolerated and highly effective in the treatment of severe diarrhea, e.g. in AIDS patients. The preparation is spray-dried and stable at 2-8 degrees C. *

PMID: 2313232 [PubMed - indexed for MEDLINE]

* note: This perfectly describes our colostrum, which is take from hundreds of animals with high exposure to humans and therefore has high antibody titres, and is processed in low heat. 

Original Article

Treatment of diarrhoea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrum 

J. A. Rump, R. Arndt, A. Arnold, C. Bendick, H. Dichtelmüller, M. Franke, E. B. Helm, H. Jäger, B. Kampmann and P. Kolb, et al.


Diarrhea and weight loss are found in more than 50% of patients with the acquired immunodeficiency syndrome (AIDS). In some patients the symptoms can be very severe, leading to death even in the absence of opportunistic infections. In 30% of these patients, enteric pathogens cannot be identified, and approximately only half of the identifiable etiologic agents of diarrhea in patients infected with the human immunodeficiency virus (HIV) were treatable with antibiotics. Immunoglobulins from bovine colostrum (Lactobin, Biotest, Dreieich, FRG) contain high titers of antibodies against a wide range of bacterial, viral and protozoal pathogens as well as against various bacterial toxins. Lactobin (LIG) is quite resistant to 24-h incubation with gastric juice. In a multi-center pilot study 37 immunodeficiency patients with chronic diarrhea [29 HIV-infected patients, 2 patients with common variable immunodeficiency (CVID), one unidentified immunodeficiency, five patients with graft versus host disease (GvHD) following bone marrow transplantation] were treated with oral LIG (10 g/day for 10 days). 
Good therapeutic effects were observed. Out of 31 treatment periods in 29 HIV-infected patients 21 gave good results leading to transient (10 days) or long-lasting (more than 4 weeks) normalization of the stool frequency. The mean daily stool frequency decreased from 7.4 to 2.2 at the end of the treatment. Eight HIV-infected patients showed no response. The diarrhea recurred in 12 patients within 4 weeks (32.4%), while 19 patients were free of diarrhea for at least 4 weeks (51.3%). In 5 patients intestinal cryptosporidiosis disappeared following oral LIG treatment. LIG treatment was also beneficial in 4 out of 5 GvHD patients. No serious side effects were recorded in any of the treated patients.

Key words Diarrhea - Colostrum-acquired immunodeficiency syndrome - Human immunodeficiency virus – Cryptosporidiosis

Journal of Molecular Medicine 
Volume 71, Number 1, 42-45, DOI: 10.1007/BF00210962 

Original Articles
A preparation from bovine colostrum in the treatment of HIV-positive patients with chronic diarrhea 

A. Plettenberg, A. Stoehr, H. -J. Stellbrink, H. Albrecht and W. Meigel

The Role of Colostrum Proline-Rich Polypeptides in Human Immunological and Neurological HealthAndrew Keech

In a prospective, open, uncontrolled study 25 patients infected with the human immunodeficiency virus with chronic refractory diarrhea and either confirmed cryptosporidiosis (n=7) or absence of demonstrable pathogenic organisms (n =18) were treated with a daily oral dose of 10 g of an immunoglobulin preparation from bovine colostrum over a period of 10 days. Among the 7 patients with cryptosporidiosis, this treatment led to complete remission in 3 and partial remission in 2. Among the 18 patients with diarrhea and negative stool culture, complete remission of diarrhea was obtained in 7 and partial remission in 4. In the remaining 2 patients with cryptosporidiosis and the 7 patients with diarrhea but no demonstrable pathogens treatment produced no significant improvement of the diarrhea. Subsequent doubling of the Lactobin dose (2 × 10 g daily) in 8 of the non-responders led to complete remission in one case and at least partial remission in a further 4 patients. 
Treatment of refractory diarrhea with 10 g immunoglobulins from bovine colostrum per day constitutes an important therapeutic approach and led to complete (40%) or partial (24%) remission of diarrhea in 64% of the patients described here.

Key words AIDS - Diarrhea - Bovine colostrum – Cryptosporidiosis

Collected and compiled by Donna Crow for
Providing pure colostrum obtained from hundreds of cows with high anti-body content, processed in low heat and spray dried. This is the purest and most potent colostrum available, worldwide. We also offer the best price.